Novel vitamin d analogues

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 401/00 (2006.01) A61K 31/59 (2006.01) B01J 19/08 (2006.01) C07D 309/12 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2227938

A class of compounds which show anti-inflammatory and immunomodulating effects is provided herein. This class of compounds is represented by a compound of Formula 1 Image wherein Q stands for a C1 -C8 hydrocarbylene diradical, R stands for hydrogen or C1-C6 hydrocarbyl, or wherein the two R Groups, taken together with the carbon atom bearing the hydroxy group can form a C3 -C8 carbocyclic ring.

Composés de formule (I) dans laquelle Q est un diradical hydrocarbylène C1-C8, R est hydrogène ou hydrocarbyle C1-C6, ou bien deux groupes R pris ensemble avec l'atome de carbone portant le groupe hydroxy peuvent former un noyau carbocylique C3-C8. Lesdits composés possèdent des effets anti-inflammatoires et immunomodulateurs; ils sont également extrêmement actifs pour induire la différentiation et inhiber la prolifération non désirée de certaines cellules.

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