C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 491/22 (2006.01) A61K 31/519 (2006.01) A61P 1/00 (2006.01) A61P 11/00 (2006.01) A61P 13/10 (2006.01) A61P 15/00 (2006.01) A61P 31/10 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2563502
A water-soluble prodrug represented by the following general formula (1) (wherein R1 represents hydrogen or C1-6 alkyl; W represents a divalent group containing tertiary amino or a divalent group containing sulfonyl; and Y represents a residue of a compound having an alcoholic hydroxy group and represented by Y-OH), a pharmaceutically acceptable salt of the prodrug, or a hydrate or solvate of either.
Un promédicament soluble dans l~eau représenté par la formule générale suivante (1) (dans laquelle R?1¿ représente l~hydrogène ou C¿1-6? alkyl ; W représente un groupe divalent contenant de l~amino tertiaire ou un groupe divalent contenant du sulfonyl, et Y représente un résidu d'un composé ayant un groupe hydroxy alcoolique et représenté par Y-OH), un sel acceptable pharmaceutiquement du promédicament ou une hydrate ou un solvate de l~un ou de l~autre.
Ohwada Jun
Ozawa Sawako
Umeda Isao
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Chugai Seiyaku Kabushiki Kaisha
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