C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/02 (2006.01) C07F 5/02 (2006.01) G01N 33/533 (2006.01) G01N 33/58 (2006.01)
Patent
CA 2493104
The invention relates to compositions and methods useful in the labeling and identification of proteins. The invention provides for highly soluble zwitterionic dye molecules where the dyes and associated side groups are non- titratable and maintain their net zwitterionic character over a broad pH range, e.g. between pH 3 and 12. These dye molecules find utility in a variety of applications, including use in the field of proteomics.
L'invention porte sur des compositions et procédés servant au marquage et à l'identification of protéines et en particulier sur des molécules de colorant zwittérionique très solubles, lesdits colorants et les groupes latéraux associés n'étant pas titrables et conservant leur caractère zwittérionique sur une large plage de pH, par exemple entre pH 3 et 12. Ces molécules marqueuses peuvent servir dans nombre d'applications y compris dans le domaine de la protéomique.
Dratz Edward A.
Grieco Paul A.
Montana State University
Smart & Biggar
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