Ntn-2 member of tnf ligand family

Details Ntn-2 member of tnf ligand family Ntn-2 member of tnf ligand family

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) C07K 14/52 (2006.01) C07K 14/525 (2006.01) C07K 16/24 (2006.01) C07K 19/00 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2292899

HUMAN NTN-2 polypeptides and related nucleic acids are provided. Included are HUMAN NTN-2 polypeptides comprising a HUMAN NTN-2 domain having specific HUMAN NTN-2 activity. The polypeptides may be produced recombinantly from transfomed host cells with subject nucleic acids. Also provided are specific binding agents and methods of making and using the subject compositions.

Cette invention se rapporte aux polypeptides dits "NTN-2 HUMAIN" et à leurs acides nucléiques associés. Elle se rapporte aux polypeptides NTN-2 HUMAINS comportant un domaine NTN-2 HUMAIN possédant une activité spécifique de NTN-2 HUMAIN. Il est possible de produire ces polypeptides par recombinaison à partir de cellules hôtes transformées en utilisant les acides nucléiques de la présente invention. Cette invention se rapporte également à des agents de liaison spécifiques et à des procédés de fabrication et d'utilisation de compositions contenant ces polypeptides.

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