Nuclear factors associated with transcriptional regulation

Details Nuclear factors associated with transcriptional regulation Nuclear factors associated with transcriptional regulation

C - Chemistry, Metallurgy

12

N

530/13, 167/139,

C12N 15/09 (2006.01) C07H 21/04 (2006.01) C07K 14/47 (2006.01) C07K 16/42 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01) C12P 21/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/68 (2006.01)

Patent

CA 1340999

Constitutive and tissue-specific protein factors which bind to transcriptional regulatory elements of Ig genes (promoter and enhancer) are described. The factors were identified and isolated by an improved assay for protein-DNA binding. Genes encoding factors which positively regulate transcription can be isolated and employed to enhance transription of Ig genes.

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