Nuclear receptor binding agents

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 217/24 (2006.01) A61K 31/472 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2676066

The present invention relates to a novel class of nuclear receptor binding agents (NRBAs). The NRBAs are applicable for use in the prevention and/or treatment of a variety of diseases and conditions including prevention and treatment of cancers such as prostate and breast cancer, osteoporosis, hormone-related diseases, inflammatory diseases, oxidative stress related disorders such as Parkinson's and stroke, neurological disorders, ophthalamic disorders, cardiovascular disease, and obesity.

La présente invention concerne une nouvelle classe d'agents se liant aux récepteurs nucléaires (NRBA). Les NRBA sont destinés à une utilisation dans la prévention et/ou le traitement d'une variété de maladies et de conditions comprenant la prévention et le traitement de cancers tels que le cancer de la prostate et le cancer du sein, l'ostéoporose, les maladies associées aux hormones, les maladies inflammatoires, les troubles associés au stress oxydatif tels que la maladie de Parkinson et l'accident vasculaire cérébral, les troubles neurologiques, les troubles ophtalmiques, les maladies cardiovasculaires, et l'obésité.

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