Nuclear targeting by means of bacterial proteins

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/62 (2006.01) A61K 31/7088 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01) C07K 19/00 (2006.01) C12N 15/90 (2006.01)

Patent

CA 2309640

A nuclear delivery construct comprises: (i) protein H or a fragment or derivative thereof that is capable of being targeted to the nucleus of a eukaryotic cell; and associated therewith (ii) one or more other components whose targeting to the nucleus of the eukaryotic cell is desired.

Cette construction d'apport nucléaire comprend: (i) une protéine H -ou un fragment ou dérivé de celle-ci-, capable d'être dirigée sur le noyau d'une cellule eucaryote et à laquelle on a associé (ii) un ou plusieurs constituants que l'on souhaite également diriger sur le noyau de la cellule eucaryote.

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