C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/11 (2006.01) A61K 31/7088 (2006.01) A61K 31/713 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2614531
Isolated oligonucleotides capable of down-regulating a level of H19 mRNA in cancer cells are disclosed. Articles of manufacture comprising agents capable of downregulating H19 mRNA in combination with an additional anti-cancer treatment are disclosed as well as methods of treating cancer by administering same.
La présente invention décrit des oligonucléotides isolés susceptibles de réguler à la baisse le niveau d'ARNm H19 dans les cellules cancéreuses. La présente invention décrit également des articles manufacturés comprenant des agents susceptibles de réguler à la baisse l'ARNm H19 combinés à un traitement anticancéreux supplémentaire, de même que des méthodes de traitement du cancer par l'administration desdits articles.
Hochberg Avraham
Matouk Imad
Ridout & Maybee Llp
Yissum Research And Development Company Of The Hebrew University
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