Nucleic acid amplification oligonucleotides and probes to...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2209991

The present invention discloses hybridization assay probes, amplification primers, nucleic acid compositions and methods useful for detecting Borrelia nucleic acids. Hybridization assay probes and amplification primers that selectively detect Lyme disease-associated Borrelia and distinguish those Borrelia from Borrelia hermsii are disclosed. Other hybridization probes selectively detect Borrelia hermsii and not Lyme disease-associated Borrelia are also described.

L'invention porte sur des sondes de dosage d'hybridation, des amorces d'amplification, des compositions d'acides nucléiques et des procédés utiles dans la détection des acides nucléiques de Borrelia; sur des sondes de dosage d'hybridation et des amorces d'amplification détectant sélectivement les Borrelia associées à la maladie de Lyme et permettant de distinguer les Borrelia des Borrelia hermsii; ainsi que sur d'autres sondes d'hybridation détectant sélectivement les Borrelia hermsii et non les Borrelia associés à la maladie de Lyme.

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