Nucleic acid analogs with a chelating functionality

Details Nucleic acid analogs with a chelating functionality Nucleic acid analogs with a chelating functionality

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) C07K 2/00 (2006.01) C07K 14/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2176745

A nucleic acid analog comprising a polymeric strand which includes a sequence of ligands bound to a backbone made up of linked backbone moieties, which analog is capable of hybridization to a nucleic acid of complementary sequence, further comprising a chelating moiety capable of binding at least one metal ion by chelation.

Un analogue d'acide nucléique comprend un brin polymère incluant une séquence de ligands liée à un squelette constitué de fractions de squelette reliées. Cet analogue peut s'hybrider avec un acide nucléique à séquence complémentaire et il comprend en outre une fraction de chélation pouvant se lier par chélation à au moins un ion métallique.

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