A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/00 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01) C12N 15/86 (2006.01)
Patent
CA 2420990
A novel gene (designated 85P1B3) and its encoded protein are described. While 85P1B3 exhibits tissue specific expression in normal adult tissue, it is aberrantly expressed in multiple cancers including set forth in Table 1. Consequently, 85P1B3 provides a diagnostic and/or therapeutic target for cancers. The 85P1B3 gene or fragment thereof, or its encoded protein or a fragment thereof, can be used to elicit an immune response.
L'invention concerne un nouveau gène (désigné sous le nom 85P1B3) et sa protéine codée. Alors que le 85P1B3 présente une expression spécifique de tissu dans un tissu adulte normal, il s'exprime de manière aberrante dans de multiples cancers, y compris ceux mentionnés dans le tableau 1. En conséquence, le 85P1B3 permet d'établir un diagnostic et/ou de mettre au point un agent thérapeutique pour lutter contre les cancers. Le gène 85P1B3 ou un fragment de celui-ci ou sa protéine codée ou un fragment de celle-ci peuvent servir à éliciter une réaction immunologique.
Afar Daniel
Challita-Eid Pia
Faris Mary
Ge Wangmao
Hubert Rene S.
Agensys Inc.
Fetherstonhaugh & Co.
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