Nucleic acid-based tests for rhd typing, gender...

Details Nucleic acid-based tests for rhd typing, gender... Nucleic acid-based tests for rhd typing, gender...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12P 19/34 (2006.01) C07H 21/04 (2006.01)

Patent

CA 2677517

The invention in part provides nucleic acid-based assays, which are particularly useful for non-invasive prenatal testing. The invention in part provides compositions and methods for RhD typing, detecting the presence of fetal nucleic in a sample, determining the relative amount of fetal nucleic acid in a sample and determining the sex of a fetus, wherein each of the assays may be performed alone or in combination.

L'invention concerne des épreuves biologiques à base d'acide nucléique. Ces épreuves biologiques sont particulièrement utiles dans des tests prénataux non invasifs. Un aspect de l'invention concerne des compositions et des procédés de typage RhD, de détection de la présence d'acide nucléique foetal dans un échantillon, de détermination de la quantité relative de l'acide nucléique foetal dans un échantillon et de détermination du sexe d'un foetus, chaque épreuve biologique pouvant être effectuée seule ou de manière combinée.

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