Nucleic acid binding proteins

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) C07K 14/47 (2006.01) C12N 9/22 (2006.01) C12N 15/10 (2006.01) C12N 15/62 (2006.01) C12Q 1/48 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2323064

The invention provides a method for producing a zinc finger polypeptide which binds to a target nucleic acid sequence containing a modified base but not to an identical sequence containing an equivalent unmodified base.

L'invention concerne une méthode permettant de produire un polypeptide à doigt à zinc destiné à se fixer à une séquence d'acide nucléique cible contenant une base modifiée, mais pas à une séquence identique renfermant une base équivalente non modifiée.

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