Nucleic acid catalysts with endonuclease activity

Details Nucleic acid catalysts with endonuclease activity Nucleic acid catalysts with endonuclease activity

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 31/70 (2006.01) C07H 21/02 (2006.01) C12N 9/00 (2006.01) C12N 15/55 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2304813

Catalytic nucleic acids, i.e. ribozymes, with new motifs giving an altered endoclease specificity, methods of screening, synthesis and expression, and uses thereof in modulating gene expression.

L'invention concerne, d'une part, des molécules d'acides nucléiques avec de nouveaux motifs, qui possèdent une activité catalytique et, d'autre part, des procédés de synthèse et d'utilisation de ces molécules.

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