Nucleic acid chelate conjugate as therapeutic and diagnostic...

Details Nucleic acid chelate conjugate as therapeutic and diagnostic... Nucleic acid chelate conjugate as therapeutic and diagnostic...

C - Chemistry, Metallurgy

12

N

167/202, 195/1.1

C12N 15/00 (2006.01) C07H 21/00 (2006.01)

Patent

CA 1319119

38 24439/SGEN-2 NUCLEIC ACID CHELATE CONJUGATE AS THERAPEUTIC AND DIAGNOSTIC AGENTS ABSTRACT OF THE DISCLOSURE Novel conjugates are provided comprising, in particular, stable nucleotide sequences joined to a chelating agent. The conjugates find use in inhibiting expression of mRNA, in killing pathogens, and in providing selection for particular classes of cells or killing particular classes of cells. Polyamine, polycarboxylic acid, chelating agents are employed in the conjugates as exemplary.

586040

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