Nucleic acid constructs including a novel t-cell active...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/11 (2006.01) A61K 31/7115 (2006.01) A61K 35/14 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/554 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2419251

An isolated nucleic acid is disclosed, including a promoter sequence being transcriptionally functional in a T-lymphocyte undergoing activation and transcriptionally less functional in the T-lymphocyte prior to the activation.

L'invention concerne un acide nucléique isolé comprenant une séquence promoteur fonctionnelle sur le plan transcriptionnel dans un lymphocyte T soumis à une activation et moins fonctionnelle sur le plan transcriptionnel dans le lymphocyte T avant son activation.

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