Nucleic acid-containing polymerizable complex

Details Nucleic acid-containing polymerizable complex Nucleic acid-containing polymerizable complex

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) C07H 19/00 (2006.01) C07H 21/02 (2006.01)

Patent

CA 2283798

Disclosed is a polymerizable complex containing a covalently attached nucleic acid molecule which, under appropriate conditions, is capable of copolymerization with a second polymerizable ethylene-containing monomer unit to form a polymerized layer. The polymerized layer containing attached nucleic acid is useful in a variety of contexts including, for example, hybridization assays. The polymerized layer containing the covalently attached nucleic acid molecule can be formed into a variety of shapes, or attached to a formed material through appropriate chemistry.

L'invention porte sur un complexe polymérisable contenant une molécule d'acide nucléique liée par covalence qui, dans certaines conditions, est susceptible de copolymérisation avec une second unité monomérique polymérisable contenant de l'éthylène pour former une couche polymérisée. La couche polymérisée contenant l'acide nucléique lié sert dans des contextes divers, notamment pour les dosages d'hybridation. La couche polymérisée contenant la molécule d'acide nucléique liée par covalence peut être réalisée sous des formes diverses ou liée à un matériau formé par des méthodes chimiques appropriées.

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