Nucleic acid-coupled colorimetric analyte detectors

Details Nucleic acid-coupled colorimetric analyte detectors Nucleic acid-coupled colorimetric analyte detectors

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C12M 1/00 (2006.01) C12N 11/00 (2006.01) C12N 15/09 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2330937

The present invention relates to methods and compositions for the direct detection of analytes and membrane conformational changes through the detection of color changes in biopolymeric materials. In particular, the present invention provides for the direct colorimetric detection of analytes using nucleic acid ligands at surfaces or polydiacetylene liposomes and related molecular layer systems.

L'invention concerne des procédés et des compositions servant à effectuer une détection directe de substances à analyser et de modifications de la conformation d'une membrane par détection de modifications de couleurs dans des matériaux biopolymères. Elle concerne, en particulier, la détection colorimétrique directe de substances à analyser au moyen de ligands d'acides nucléiques au niveau de surfaces de liposomes de polydiacétylène et de systèmes apparentés de couches moléculaires.

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