Nucleic acid delivery using modified chitosans

Details Nucleic acid delivery using modified chitosans Nucleic acid delivery using modified chitosans

A - Human Necessities

61

K

A61K 48/00 (2006.01) C12N 15/88 (2006.01)

Patent

CA 2751268

The present invention is directed to the delivery of nucleic acids in a non- viral vector to cells by positively charged chitosan deriva-tives, including but not limited to chi-tosan-arginine, chitosan-lysine and chitosan-histidine.

La présente invention porte sur l'administration d'acides nucléiques dans un vecteur non viral à des cellules par dérivés de chitosane chargées positivement, comprenant mais sans s'y limiter, la chitosane-arginine, la chitosane-lysine et la chitosane-histidine.

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