Nucleic acid enzymes and complexes and methods for their use

Details Nucleic acid enzymes and complexes and methods for their use Nucleic acid enzymes and complexes and methods for their use

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C12N 9/00 (2006.01) C12N 15/09 (2006.01)

Patent

CA 2682612

The present invention relates to methods that utilise multi-component nucleic acid complex (MNA complex) cascades. The MNA complexes may have cleavage or ligase activity. Further, the invention provides cascades which may include one or more DNAzymes. The invention also provides methods which use these cascades for the identification, detection and quantification of targets.

La présente invention concerne des procédés qui utilisent des cascades de complexes d'acides nucléiques multi-composants (complexes MNA). Les complexes MNA peuvent avoir une activité de clivage ou de ligase. De plus, l'invention fournit des cascades qui peuvent inclure une ou plusieurs ADNzymes. L'invention concerne également des procédés qui utilisent ces cascades en vue de l'identification, la détection et la quantification de cibles.

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