C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/49 (2006.01) C07K 14/155 (2006.01) C07K 16/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/569 (2006.01)
Patent
CA 2193997
Nucleotide fragments from caprine arthritis-encephalitis virus (CAEV) env gene, corresponding peptide fragments, and uses thereof in screening for viral caprine arthritis-encephalitis, are disclosed. Antibodies to peptide fragments and uses thereof for diagnosing viral arthritis-encephalitis are also disclosed. Said nucleic acid fragments code for a peptide fragment including at least one CAEV Env protein segment comprising at least one immunodominant epitope selected from the transmembrane region of said protein, and include 15- 255 nucleotides.
Fragments nucléotides issus du gène env du virus de l'arthrite et de l'encéphalite caprine (VAEC ou CAEV : caprine arthritis-encephalitis virus) et fragments peptidiques correspondants et leurs applications au dépistage de l'encéphalite et de l'arthrite virale caprine. Anticorps anti-fragments peptidiques ainsi que leurs applications au diagnostic de l'encéphalite et de l'arthrite virale. Lesdits fragments d'acide nucléique codent pour un fragment peptidique includant au moins un segment de protéine Env du VAEC comprenant au moins un épitope immunodominant, sélectionné dans la région transmembranaire de ladite protéine, lesquels fragments d'acide nucléique comprennent entre 15 et 255 nucléotides.
Bertoni Giuseppe
Pancino Gianfranco
Peterhans Ernst
Sonigo Pierre
Centre National de La Recherche Scientifique - Cnrs
Marcus & Associates
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