Nucleic acid immunological composition for human...

A - Human Necessities – 61 – K

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A61K 39/155 (2006.01) A61P 31/14 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2624291

There is provided an immunological composition that comprises a nucleic acid vector which includes a promoter region operably linked to a coding sequence encoding the human metapneumovirus F antigen or the human metapneumovirus G antigen. The immunological composition is useful for administering to an individual to elicit an immune responce to human metapneumovirus in the individual and for the generation of diagnostic reagents for hMPV.

L'invention concerne une composition immunologique comprenant un vecteur d'acides nucléiques qui comprend une région promoteur fonctionnellement liée à une séquence de codage codant l'antigène F ou l'antigène G du métapneumovirus humain ("human metapneumovirus" ou hMPV). La composition immunologique de l'invention peut être administrée à un individu afin de provoquer une réponse immunitaire au métapneumovirus humain chez l'individu et de produire des réactifs diagnostiques du hMPV.

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