Nucleic acid labeling compounds

Details Nucleic acid labeling compounds Nucleic acid labeling compounds

C - Chemistry, Metallurgy

07

H

C07H 19/06 (2006.01) C07H 19/10 (2006.01) C07H 21/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2507573

Nucleic acid labeling compounds containing heterocyclic derivatives are disclosed. The heterocyclic derivative containing compounds are synthesized by condensing a heterocyclic derivative with a cyclic group (e.g. a ribofuranose derivative). The labeling compounds are suitable for enzymatic attachment to a nucleic acid, either terminally or internally, to provide a mechanism of nucleic acid detection.

L'invention concerne des composés de marquage d'acide nucléique contenant des dérivés hétérocycliques. Ces composés sont synthétisés par condensation d'un dérivé hétérocyclique avec un groupe cyclique (par exemple un dérivé de la ribofuranose). Ces composés de marquage conviennent pour la liaison enzymatique avec un acide nucléique, en position terminale ou interne, pour créer un mécanisme de détection des acides nucléiques.

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