Nucleic acid labeling compounds

Details Nucleic acid labeling compounds Nucleic acid labeling compounds

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) C07H 19/04 (2006.01) C07H 19/052 (2006.01) C07H 19/06 (2006.01) C07H 19/10 (2006.01) C07H 19/12 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2339016

Nucleic acid labeling compounds containing heterocyclic derivatives are disclosed. The heterocyclic derivative containing compounds are synthesized by condensing a heterocyclic derivative with a cyclic group (e.g. a ribofuranose derivative). The labeling compounds are suitable for enzymatic attachment to a nucleic acid, either terminally or internally, to provide a mechanism of nucleic acid detection.

Cette invention se rapporte à des composés de marquage d'acides nucléiques, qui contiennent des dérivés hétérocycliques et que l'on synthétise en condensant un dérivé hétérocyclique avec un groupe cyclique (par exemple un dérivé ribofuranose). Ces composés de marquage sont propres à former une liaison enzymatique avec un acide nucléique en position soit terminale soit interne, pour créer un mécanisme de détection des acides nucléiques.

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