Nucleic acid labeling compounds

Details Nucleic acid labeling compounds Nucleic acid labeling compounds

C - Chemistry, Metallurgy

07

D

C07D 413/04 (2006.01) C07D 239/46 (2006.01) C07D 403/04 (2006.01) C07D 405/04 (2006.01) C07D 409/04 (2006.01) C07H 7/00 (2006.01) C07H 7/06 (2006.01) C07H 19/06 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2440615

Nucleic acid labeling compounds are disclosed. The compounds are synthesized by condensing a heterocyclic derivative with a cyclic group (e.g. a ribofuranose derivative). The labeling compounds are suitable for enzymatic attachment to a nucleic acid, either terminally or internally, to provide a mechanism of nucleic acid detection.

Cette invention concerne des composés de marquage des acides nucléiques. La synthèse de ces composés se fait en condensant un dérivé hétérocycliques avec un groupe cyclique (tel qu'un dérivé de la ribofuranose). Ces composés de marquage conviennent pour la liaison enzymatique avec un acide nucléique, de manière soit terminale, soit interne, et offrent un mécanisme de détection des acides nucléiques.

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