Nucleic acid mediated rna tagging and rna revision

Details Nucleic acid mediated rna tagging and rna revision Nucleic acid mediated rna tagging and rna revision

C - Chemistry, Metallurgy

12

N

C12N 15/11 (2006.01) A61K 48/00 (2006.01) C07K 14/805 (2006.01) C12N 9/00 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2312006

A method of identifying accessible regions in a target RNA molecule using trans-splicing nucleic acid molecules is disclosed. Also disclosed is a method of revising mutant globin gene sequences using trans-splicing nucleic acid molecules and a method of tagging nucleic acid molecules with Tag moieties using trans-splicing nucleic acid molecules.

Procédé permettant d'identifier des régions accessibles dans une molécule d'ARN ciblée au moyen de molécules d'acides nucléiques de trans-épissage. Procédé de révision de séquences mutantes de gènes de globine au moyen de molécules d'acides nucléiques de trans-épissage et procédé de marquage de molécules d'acides nucléiques par des fractions de marquage au moyen de molécules d'acides nucléiques de trans-épissage.

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