Nucleic acid molecule of a biosynthetic cluster encoding non...

Details Nucleic acid molecule of a biosynthetic cluster encoding non... Nucleic acid molecule of a biosynthetic cluster encoding non...

C - Chemistry, Metallurgy

07

K

C07K 14/195 (2006.01) C07K 11/02 (2006.01)

Patent

CA 2751831

The present invention relates to the provision of a polynucleotide comprising one or more functional fragments of a biosynthetic gene cluster involved in the production of a compound of formula (I) or (P). The present invention also provides a method of preparing a compound of formula (I) or (I) or of formula (II) to (VII), (XI) to (XIV) and (XVII) and (XVIII). Moreover, the use of such compound as a pharmaceutical composition is also provided in the present invention.

La présente invention concerne l'alimentation en un polynucléotide comprenant un ou plusieurs fragments fonctionnels d'un agrégat génétique biosynthétique impliqué dans la production d'un composé de formule (I) ou (I'). La présente invention concerne également un procédé de préparation d'un composé de formule (I) ou (I') ou de formule (II) à (VII), (XI) à (XIV) et (XVII) et (XVIII). De plus, l'invention concerne également l'utilisation d'un tel composé comme composition pharmaceutique.

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