Nucleic acid molecules and polypeptides for immune modulation

Details Nucleic acid molecules and polypeptides for immune modulation Nucleic acid molecules and polypeptides for immune modulation

A - Human Necessities

61

K

A61K 39/275 (2006.01) C07K 14/065 (2006.01)

Patent

CA 2424983

The invention provides gp38 polypeptides, which play a role in immunomodulation, nucleic acid molecules encoding these polypeptides, and therapeutic and diagnostic methods employing these polypeptides and nucleic acid molecules. The invention also provides methods for identifying compounds that modulate the biological activities of gp38 nucleic acid molecules and polypeptides, and therapeutic methods employing these compounds.

Cette invention, qui a trait à des polypeptides gp38, jouant un rôle immunodulateur et à des molécules d'acide nucléique codant ces polypeptides, concerne également des méthodes diagnostiques thérapeutiques utilisant ces polypeptides ainsi que ces molécules nucléotidiques. Elle porte, de surcroît, sur des techniques d'identification de composés modulant l'activité biologique des molécules nucléotidiques et des polypeptides gp38 ainsi que sur des méthodes thérapeutiques faisant intervenir ces composés.

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