Nucleic acid molecules encoding a transmembran serine...

Details Nucleic acid molecules encoding a transmembran serine... Nucleic acid molecules encoding a transmembran serine...

C - Chemistry, Metallurgy

12

N

C12N 9/64 (2006.01) C12N 15/57 (2006.01) C12N 15/74 (2006.01) C12N 15/79 (2006.01) C12Q 1/37 (2006.01)

Patent

CA 2442089

Provided herein are type II transmembrane serine protease 9 (MTSP9) polypeptides. Zymogen and activated forms of these polypeptides as well as single and two chain forms of the protease domaine are also provided. Methods using the polypeptides to identify compounds that modulate the protease activity of an MTSP9 are provided.

La présente invention concerne des polypeptides de sérines protéases transmembranaires 9 (MTSP9), les formes zymogènes et activées de ces polypeptides ainsi que les formes monocaténaires et bicaténaires du domaine protéase. Des procédés d'utilisation de ces polypeptides pour identifier des composés qui modulent l'activité protéase d'une MTSP9 sont également présentées.

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