C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 14/00 (2006.01) C12N 5/10 (2006.01) C12N 15/11 (2006.01) C12N 15/63 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2555208
Disclosed herein are novel nucleic acid molecules encoding murine low-voltage activated calcium channel proteins, designated - .alpha.1H, encoded proteins, vectors, host cells transformed therewith, as well as pharmaceutical compositions. Methods of using any of the foregoing, e.g., methods for screening for candidate agonists or antagonists utilizing the novel protein isoforms are also disclosed.
De nouvelles molécules d'acide nucléique codant des protéines murines à canal de calcium activé faible tension, des .alpha.1H spécialisés, des protéines codées, des vecteurs, des cellules hôtes transformées, ainsi que des compositions pharmaceutiques. Des procédés d'utilisation d'un des éléments suivants, notamment des procédés de dépistage d'agonistes ou d'antagonistes candidats utilisant les nouvelles isoformes protéiques.
Connolly Thomas M.
Uebele Victor N.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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