Nucleic acid molecules encoding serine protease cvsp14, the...

Details Nucleic acid molecules encoding serine protease cvsp14, the... Nucleic acid molecules encoding serine protease cvsp14, the...

C - Chemistry, Metallurgy

12

N

C12N 9/64 (2006.01) C12N 15/57 (2006.01) C12N 15/63 (2006.01) C12N 15/70 (2006.01) C12N 15/74 (2006.01) C12N 15/79 (2006.01) C12N 15/80 (2006.01) C12N 15/85 (2006.01) C12Q 1/37 (2006.01)

Patent

CA 2441378

Provided herein are polypeptides designated CVSP14 polypeptides that exhibit protease activity as a single chain or as an activated two chain form. Methods using the polypeptides to identify compounds that modulate the protease activity thereof are provides. The polypeptides also serve as tumor markers.

L'invention porte sur des polypeptides appelés polypeptides CVSP14 qui présente l'activité de la protéase sous forme d'une chaîne unique ou sous une forme activée à deux chaînes. L'invention porte également sur des procédés utilisant ces polypeptides pour identifier des composés qui modulent l'activité de la protéase. Les polypeptides de cette invention peuvent également être utilisés comme marqueurs tumoraux.

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