Nucleic acid molecules, polypeptides, antibodies and...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/44 (2006.01) A61K 31/7088 (2006.01) A61K 31/7115 (2006.01) A61K 39/145 (2006.01) A61K 47/26 (2006.01) A61K 47/48 (2006.01) A61P 31/16 (2006.01) C07H 21/00 (2006.01) C07K 14/11 (2006.01) C07K 16/10 (2006.01) C07K 17/00 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2517074

Polynucleotides and polypeptides which participate in influenza virus infection of cells and nucleic acid molecules, which include a polynucleotide sequence capable of specifically binding the polypeptides of the present invention. Also provided are methods of using such nucleic acid molecules, polynucleotides and antibodies directed thereagainst for diagnosing, treating and preventing influenza virus infection.

L'invention porte sur des polynucléotides et sur des polypeptides qui participent à l'infection par le virus de la grippe des cellules et des molécules d'acide nucléique, et qui comprennent une séquence polynucléotidique capable de se lier de manière spécifique aux polypeptides de la présente invention. L'invention porte également sur des procédés d'utilisation de ces molécules d'acide nucléique, des polynucléotides et des anticorps dirigés contre ceux-ci, dans le diagnostic, le traitement et la prévention de l'infection par le virus de la grippe.

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