Nucleic acid probe for the detection of salmonella human...

Details Nucleic acid probe for the detection of salmonella human... Nucleic acid probe for the detection of salmonella human...

C - Chemistry, Metallurgy

12

N

195/1.12, 150/8.

C12N 15/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2009708

Abstract of the Invention Described herein are nucleic acid probes that can detect Salmonella human pathogens. The probes are generated from the nucleotide sequences of a gene encoding a virulence factor involved in the pathogenesis of Salmonella, especially the Type 1 fimbriae protein. The most preferred lengths of the probes range from about 20 to about 100 nucleotide bases in length. The probes are highly specific and sensitive for detecting Salmonella organisms pathogenic to humans. They are thus clinically useful in the detection of infection in diarrhea specimens. Additionally, they may be used in the detection of food-borne Salmonella, the causative agent of most salmonellosis in humans. ORD-77

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