Nucleic acid probes and methods for detecting cryptococcus...

Details Nucleic acid probes and methods for detecting cryptococcus... Nucleic acid probes and methods for detecting cryptococcus...

C - Chemistry, Metallurgy

07

H

195/1.12, 150/8.

C07H 21/00 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2025179

Abstract Nucleic acid probes are described for detecting yeasts capable of causing cryptococcosis, specifically Cryptococcus neoformans. The preferred probes are complementary to the ribosomal ribonucleic acid sequences unique to Cryptococcus neoformans, and as such can detect the rRNA, rDNA, or polymerase chain reaction amplification products of these genes. The detection of the etiological agent of human cryptococcosis, and tests for making a clinical diagnosis of this disease utilizing specific rRNA or rDNA probes are now possible.

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