Nucleic acid sequences of genes of the high mobility group...

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/12 (2006.01) C12N 5/071 (2010.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2239682

The invention relates to DNA sequences, the use thereof and the use of DNA sequences of the MAG genes or high mobility group protein genes, agents for treating various disorders including tumour disorders, for influencing vascular development and for contraception and tissue regeneration, and to suitable kits and procedures. The specified sequences, agents, applications, kits and procedures allow a specific action on molecular mechanisms common to various disorders, vascular development, contraception and tissue regeneration. This reduces the drawbacks normally observed with agents and procedures of this type.

L'invention concerne des séquences d'ADN, leur utilisation ainsi que l'utilisation de séquences d'ADN des gènes de croissance aberrante de tumeurs multiples ou des gènes des protéines du groupe à grande mobilité. L'invention concerne également des moyens pour traiter différentes affections, y compris des affections tumorales, des moyens pour agir sur le développement des vaisseaux, des moyens utilisés à des fins de contraception et de régénération des tissus ainsi que les kits et procédés correspondants. Les séquences, moyens, utilisations, kits et procédés mentionnés permettent d'exercer une action spécifique sur des mécanismes moléculaires à l'origine de différentes affections, de la contraception et de la régénération des tissus, ce qui minimise les inconvénients normalement observés avec des moyens et procédés de ce type.

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