Nucleic acid sequences that encode a cell growth regulatory...

Details Nucleic acid sequences that encode a cell growth regulatory... Nucleic acid sequences that encode a cell growth regulatory...

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) A61K 38/45 (2006.01) C07K 16/40 (2006.01) C12N 9/12 (2006.01) C12N 15/86 (2006.01) C12Q 1/48 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2263148

Compositions of matter consisting of a family of related nucleic acid sequences that encode proteins, termed Cell Growth Regulatory Proteins, that phosphorylate cell cycle targets, and methods of using the nucleotide sequences and the proteins encoded thereby, to diagnose and/or treat disease where the Cell Growth Regulatory Proteins have an apparent molecular weight of about 54.6 kdaltons.

L'invention porte sur des compositions comprenant une famille de séquences apparentées d'acides nucléique codant des protéines, appelées protéines de régulation de la prolifération cellulaire, et sur des procédés d'utilisation des séquences nucléotidiques et des protéines codées par celles-ci, ces procédés consistant à diagnostiquer et/ou traiter des maladies où les protéines de régulation de la prolifération cellulaire ont un poids moléculaire apparent d'environ 54,6 kdaltons.

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