C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
150/8.5
C12Q 1/68 (2006.01) C12Q 1/70 (2006.01)
Patent
CA 2026573
2026573 9008840 PCTABS00001 A nucleic acid test article can be used to detect a predetermined nucleic acid found in a specimen. The test article comprises a substrate having two opposing surfaces and a water-insoluble nucleic acid probe attached to at least one of the surfaces in a distinct zone thereof. The probe is composed of a water-insoluble particle to which is covalently attached an oligonucleotide which is complementary to a predetermined nucleic acid of interest. Substantially none of the probe is embedded within the surface of the substrate. Particularly useful test articles have a multiplicity of water-insoluble probes located in distinct zones on one of the substrate surfaces useful for the detection of a multiplicity of predetermined nucleic acids.
Chang Chu-An
Findlay John B.
King Marlene M.
Levenson Corey H.
Mayer Janice M.
Cetus Corporation
Chang Chu-An
Eastman Kodak Company
Findlay John B.
Gowling Lafleur Henderson Llp
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