Nucleic acids and corresponding proteins entitled 58p1d12...

Details Nucleic acids and corresponding proteins entitled 58p1d12... Nucleic acids and corresponding proteins entitled 58p1d12...

A - Human Necessities

61

K

A61K 39/395 (2006.01) C07K 16/00 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2576500

A novel gene 58P1D12 and its encoded protein, and variants thereof, are described wherein 58P1D12 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, 58P1D12 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The 58P1D12 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with 58P1D12 can be used in active or passive immunization.

La présente invention porte sur un nouveau gène 58P1D12 et sa protéine codée, et des variantes de celui-ci. 58P1D12 présente une expression spécifique du tissu dans le tissu normal d~un adulte et est exprimé de manière aberrante dans les cancers répertoriés dans le tableau 1. En conséquence, 58P1D12 offre une cible diagnostique, pronostique, prophylactique et/ou thérapeutique du cancer. Le gène 58P1D12 ou un fragment de celui-ci, ou sa protéine codée, ou des variantes ou un fragment de celle-ci, peut être utilisé pour déclencher une réponse immunitaire humorale ou cellulaire ; des anticorps ou des lymphocytes T réagissant à 58P1D12 peuvent être utilisés dans l~immunisation active ou passive.

Affiliated with

Also associated with

Rating

Nucleic acids and corresponding proteins entitled 58p1d12... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nucleic acids and corresponding proteins entitled 58p1d12..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nucleic acids and corresponding proteins entitled 58p1d12... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1756129