C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 21/04 (2006.01) A61K 31/711 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C12N 5/16 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2416676
This invention provides for an isolated nucleic acid comprising a PEG-3 promoter comprising the nucleotide sequence beginning with the guanosine (G) at position -270 and ending with the cytosine (C) at position +194 of SEQ ID NO: 1. The invention also provides for a method for identifying an agent which modulates PEG-3 promoter activity in a cell. The invention also provides for a method for treating cancer in a subject.
L'invention concerne un acide nucléique isolé comprenant un promoteur PEG-3 possédant la séquence de nucléotides commençant par guanosine (G) dans la position -270 et finissant par cytosine (C) dans la position +194 de SEQ ID NO:1. Elle concerne également un procédé servant à identifier un agent modulant l'activité du promoteur PEG-3 dans une cellule. Elle concerne également un procédé servant à traiter le cancer chez un patient.
Fisher Paul B.
Su Zao-Zhong
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
The Trustees Of Columbia University In The City Of New York
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