C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61P 1/00 (2006.01) A61P 5/00 (2006.01) A61P 27/16 (2006.01) A61P 43/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2339871
A human P2X2 purinergic receptor polypeptide is provided. Nucleic acid molecules encoding the human P2X2 receptor polypeptide, and vectors and host cells containing such nucleic acid molecules, are also provided. In addition, methods are provided for producing the P2X2 receptor polypeptide, as are methods of using such polypeptides and host cells that express the same to screen for compounds having activity on P2X2 receptor. Further, therapeutic uses involving aspects of this receptor are contemplated.
L'invention concerne un polypeptide de récepteur purinergique P2X¿2? de l'homme. L'invention traite aussi des molécules d'acide nucléique codant ledit polypeptide et des vecteurs et des cellules hôtes contenant ces molécules d'acide nucléique. En outre, l'invention a pour objet des procédés de production du polypeptide du récepteur P2X¿2?, et des procédés d'utilisation de ces polypeptides et des cellules hôtes qui expriment ces derniers afin de détecter les composés présentant une activé sur le récepteur P2X¿2?. En outre, l'invention concerne les utilisations thérapeutiques ce de récepteur.
Burgard Edward C.
Lynch Kevin J.
Metzger Randy E.
Niforatos Wende
Touma Edward B.
Abbott Laboratories
Norton Rose Or S.e.n.c.r.l.,s.r.l./llp
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