C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12Q 1/68 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2317449
A human P2X3 purinergic receptor polypeptide is provided. Nucleic acid molecules encoding the human P2X3 receptor polypeptide, and vectors and host cells containing such nucleic acid molecules, are also provided. In addition, methods are provided for producing the P2X3 receptor polypeptide, as are methods of using such polypeptides and host cells that express the same to screen for compounds having activity at the P2X3 receptor.
La présente invention concerne un polypeptide récepteur purinergique humain P2X¿3?. L'invention se rapporte également à des molécules d'acide nucléique codant ledit polypeptide récepteur humain P2X¿3?, et à des vecteurs et des cellules hôtes contenant ces molécules d'acide nucléique. L'invention concerne en outre des procédés de production du polypeptide récepteur P2X¿3? et des procédés d'utilisation de ces polypeptides et des cellules hôtes qui expriment ces derniers pour le criblage de composés déployant une activité sur le site du récepteur P2X¿3?.
Burgard Edward C.
Lynch Kevin J.
Van Biesen Tim
Abbott Laboratories
Swabey Ogilvy Renault
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