Nucleic acids encoding a functional mammalian...

Details Nucleic acids encoding a functional mammalian... Nucleic acids encoding a functional mammalian...

C - Chemistry, Metallurgy

12

P

C12P 21/06 (2006.01) C12N 1/12 (2006.01) C12N 1/20 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/70 (2006.01)

Patent

CA 2624379

The subject invention relates to the rhesus monkey P2X3 receptor, nucleic acids encoding this receptor, methods of modulating the activity of a target purinergic receptor using the P2X3 receptor and to uses of these methods. In particular, such methods may be used, for example, to accelerate the rate of resensitization of a desensitized receptor.

La présente invention se rapporte au récepteur P2X3 du singe rhésus, à des acides nucléiques codant pour ledit récepteur, à des procédés permettant de moduler l'activité d'un récepteur purinergique cible à l'aide du récepteur P2X3, et à l'utilisation desdits procédés. De tels procédés peuvent en particulier servir à augmenter, par exemple, la vitesse de resensibilisation d'un récepteur désensibilisé.

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