Nucleic acids encoding isav polypeptides

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/44 (2006.01) A01K 67/027 (2006.01) A61K 31/7088 (2006.01) A61K 48/00 (2006.01) C07K 14/11 (2006.01) C12N 15/40 (2006.01) C12N 15/85 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2442346

Infectious Salmon Anemia Virus (ISAV) nucleic acid molecules and polypeptides are disclosed, as well as host cells and transgenic fish transformed by expression vectors containing such nucleic acids. The nucleic acid molecules can encode antigenic epitopes capable of eliciting an immune response in a host cell or animal, such as an immune response against ISAV, and the polypeptides themselves can be antigenic epitopes and also induce such an immune response.

L'invention concerne des molécules d'acides nucléiques du virus de l'anémie infectieuse du saumon (ISAV) et des polypeptides, ainsi que des cellules hôtes et des poissons transgéniques transformés au moyen de vecteurs d'expression contenant lesdits acides nucléiques. Lesdites molécules d'acides nucléiques peuvent coder pour des épitopes antigènes capables de stimuler une réponse immunitaire dans une cellule hôte ou chez un animal, telles qu'une réponse immunitaire à l'encontre d'ISAV, et les polypeptides peuvent eux-mêmes être des épitopes antigènes et induire également cette réponse immunitaire.

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