Nucleic acids encoding osteoprotegerin-like proteins and...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/51 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01) C07K 16/18 (2006.01)

Patent

CA 2347293

Disclosed are osteoprotegerin-like polypeptides, nucleic acids encoding osteoprotegerin-like polypeptides, and methods of using these molecules. The osteoprotegerin-like polypeptides sequence homology to osteoprotegerin and tumor necrosis factor receptor molecules.

L'invention se rapporte à des polypeptides semblables à l'ostéoprotégérine, à des acides nucléiques codant pour ces polypeptides semblables à l'ostéoprotégérine, et à des méthodes d'utilisation de ces molécules. Elle se rapporte également à l'homologie des séquences des polypeptides semblables à l'ostéoprotégérine avec les molécules d'ostéoprotégérine et les molécules réceptrices du facteur de nécrose des tumeurs.

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