C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) C12N 15/113 (2010.01) A61K 38/00 (2006.01) A61K 38/17 (2006.01) A61P 17/02 (2006.01) C07H 21/00 (2006.01) C07K 7/06 (2006.01) C07K 7/08 (2006.01) C07K 14/47 (2006.01)
Patent
CA 2743999
The present disclosure relates to protein and peptide chemistry. More particularly, it relates to compounds, compositions and uses thereof for promoting and inhibiting angiogenesis. The peptides of the present disclosure include peptides comprising SEQ ID NOs: 1-4 which promote angiogenesis and cell proliferation. Further, the anti-angiogenic compounds of the present disclosure include antisense oligonucleotides that hybridize or are complementary to the polynucleotides of SEQ ID NOs: 5-16, and the like.
La présente invention concerne la chimie des protéines et des peptides. L'invention concerne plus particulièrement des composés, des compositions, et leurs utilisations pour favoriser et inhiber l'angiogenèse. Les peptides de la présente invention incluent des peptides comprenant les SEQ ID NOs: 1-4 qui favorisent l'angiogenèse et la prolifération cellulaire. De plus, les composés antiangiogéniques de la présente invention incluent des oligonucléotides antisens qui hybrident les polynucléotides des SEQ ID NOs: 5-16 ou qui en sont complémentaires, et analogues.
Benoit & Cote Associes Inc.
Trustees Of Tufts College
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