Nucleic acids encoding sperm antigens and reprosa-i...

Details Nucleic acids encoding sperm antigens and reprosa-i... Nucleic acids encoding sperm antigens and reprosa-i...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 39/00 (2006.01) A61K 39/395 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 5/10 (2006.01) C12N 5/16 (2006.01) C12N 15/62 (2006.01) G01N 33/50 (2006.01)

Patent

CA 2281060

Purified or recombinant peptides and polypeptides having a sequence of a human sperm protein are disclosed. Also provided are polynucleotides encoding the polypeptide, and antibodies that specifically bind the polypeptide. The novel reagents of the invention are used for diagnosis and treatment of human diseases such as immunological infertility, and in contraceptive formulations and vaccines.

L'invention concerne des peptides et polypeptides purifiés ou recombinés contenant une séquence de protéine de sperme humain. L'invention concerne également des polynucléotides codant le polypeptide et des anticorps qui fixent de manière spécifique le polypeptide. Les nouveaux réactifs de l'invention sont utilisés dans le diagnostic et le traitement de maladies humaines, telles que l'infertilité immunologique, ainsi que dans des préparations et vaccins de contraception.

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