Nucleic acids of the human abca12 gene, vectors containing...

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C07K 14/705 (2006.01)

Patent

CA 2438125

The present invention relates to a novel human ABCA12 gene as well as cDNAs encoding the novel full and short length ABCA12 proteins. The invention also relates to vectors and recombinant host cells comprising such nucleic acids, nucleotide probes and primers, and means for the detection of polymorphisms and mutations in the ABCA12 gene or in the corresponding protein produced by the allelic form of the ABCA12 gene.

L'invention concerne le gène humain ABCA12 ainsi que des ADNc codant pour les protéines ABCA12 de longueurs complètes et courtes. Elle concerne aussi des vecteurs et des cellules hôtes recombinantes contenant de tels acides nucléiques, des sondes et des amorces, ainsi que des moyens destinés à détecter des polymorphismes et des mutations du gène ABCA12 ou dans la protéine correspondante produite par la forme allélique du gène ABCA12.

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