Nucleic acids of the human abcc12 gene, vectors containing...

Details Nucleic acids of the human abcc12 gene, vectors containing... Nucleic acids of the human abcc12 gene, vectors containing...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/16 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) A61L 27/38 (2006.01) C07H 21/00 (2006.01) C07K 14/705 (2006.01) C07K 16/28 (2006.01) C12N 15/10 (2006.01) C12N 15/85 (2006.01) C12N 15/861 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2439693

The present invention relates to a novel human ABCC12 gene as well as the cDNAs encoding the novel short and long of ABCC12 proteins isoforms. The invention also relates to vectors and recombinant host cells comprising such nucleic acids, nucleotide probes and primers, and means for the detection of polymorphisms and mutations in the ABCC12 gene or in the corresponding proteins isoforms produced by the allelic form of the ABCC12 gene.

L'invention concerne un nouveau gène humain appelé ABCC12 ainsi que les ADNc codant les nouvelles isoformes courtes et longues des protéines ABCC12. Par ailleurs, l'invention concerne des vecteurs et des cellules hôtes recombinées contenant ces acides nucléiques, des sondes nucléotidiques et des amorces, ainsi que des moyens de détection de polymorphismes et de mutations dans le gène ABCC12 ou dans les isoformes des protéines correspondantes, produites par la forme allélique du gène ABCC12.

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