Nucleic acids, proteins and antibodies

A - Human Necessities – 61 – K

Patent

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Details

A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 16/18 (2006.01) C12N 5/00 (2006.01) C12N 9/00 (2006.01) C12N 9/64 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2395816

The present invention relates to novel proteins. More specifically, isolated nucleic acid molecules are provided encoding novel polypeptides. Novel polypeptides and antibodies that bind to these polypeptides are provided. Also provided are vectors, host cells, and recombinant and synthetic methods for producing human polynucleotides and/or polypeptides and antibodies. The invention further relates to diagnostic and therapeutic methods useful for diagnosing, treating, preventing and/or prognosing disorders related to these novel polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further relates to methods and/or compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.

L'invention porte: sur de nouvelles protéines: plus spécifiquement sur des molécules isolées d'acide nucléique codant pour de nouveaux polypeptides; sur de nouveaux polypeptides et anticorps se fixant à ces polypeptides; sur des vecteurs, des cellules hôtes, et des méthodes de recombinaison et de synthèse, servant à produire des polynucléotides et/ou polypeptides et anticorps humains; sur des méthodes diagnostiques et thérapeutiques permettant de diagnostiquer, traiter, prévenir et/ou pronostiquer des troubles liés à ces nouveaux polypeptides; sur des procédés de criblage permettant d'identifier les agonistes et antagonistes des polynucléotides et polypeptides de l'invention; et sur des procédés et/ou préparations inhibant ou accroissant la production et le fonctionnement des polypeptides de l'invention.

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