Nucleic acids, proteins, and antibodies

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12N 1/20 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/70 (2006.01) C12N 15/74 (2006.01)

Patent

CA 2395794

The present invention relates to novel proteins. More specifically, isolated nucleic acid molecules are provided encoding novel polypeptides. Novel polypeptides and antibodies that bind to these polypeptides are provided. Also provided are vectors, host cells, and recombinant and synthetic methods for producing human polynucleotides and/or polypeptides, and antibodies. The invention further relates to diagnostic and therapeutic methods useful for diagnosing, treating, preventing and/or prognosing disorders related to these novel polypeptides. The invention further relates to screening methods for identifying agonists and antagonists of polynucleotides and polypeptides of the invention. The present invention further relates to methods and/or compositions for inhibiting or enhancing the production and function of the polypeptides of the present invention.

L'invention concerne des protéines, et plus spécifiquement des molécules d'acides nucléiques isolées codant pour des polypeptides, ainsi que des polypeptides et des anticorps se liant à ces polypeptides. Elle concerne aussi des vecteurs, des cellules hôtes, des procédés de synthèse et de recombinaison destinés à produire des polynucléotides et/ou des polypeptides et des anticorps humains, des procédés thérapeutiques et de diagnostic permettant de diagnostiquer, traiter, empêcher et/ou pronostiquer des troubles associés à ces polypeptides. Elle concerne encore des procédés de criblage destinés à identifier des agonistes et des antagonistes des polynucléotides et des polypeptides de l'invention, ainsi que des procédés et/ou des compositions destinées à inhiber ou à augmenter la production et la fonction des polypeptides de l'invention.

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